Web11 apr. 2024 · We show that by activating using CAP, we can effectively release gentamicin from the hydrogel and also eradicate the bacteria effectively, both in the planktonic state and within a biofilm. WebWe developed a hydrogel-based encapsulation system that incorporates a biocompatible multilayer tough shell and an alginate-based core. This deployable …
Dual-Function Hydrogel Dressings with a Dynamic Exchange of …
WebIn this investigation a novel approach based on mucoadhesive superporous hydrogel hybrids (SPHHs) for topi- cal vaginal drug delivery for Metronidazole was tried. Method: SPHHs were synthesized by solution polymerization tech- nique. The synthesized SPHHs were characterized for tensile strength, swelling behavior, porosity, density, … introduction to mathematical portfolio theory
Dual-Function Hydrogel Dressings with a Dynamic Exchange of …
WebOur first design involved a twenty amino acid lysine-rich amphiphilic peptide, MAX1, which self-assembles into β-sheet rich fibrils that constitute the formation of a mechanically rigid hydrogel. 59 Solvent exposed cationic lysines on the surface of the fibrils interact with negatively-charged bacterial cell surfaces, ultimately causing membrane disruption … WebThe hydrogel loaded with bacteriophages and meropenem showed a positive result in locally reducing the infection load indicating a synergistic effect of the selected antimicrobials. Overall, our new strategy shows encouraging results for improving the treatment of antibiotic-resistant biofilm infections that are related to medical implants. Web1 sep. 2024 · The FEMI hydrogel demonstrated an accelerated MDR bacteria-infected diabetic wound healing in vivo and represents a versatile strategy for healing a broad range of tissue damages caused by diabetes. 171 Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds. U. Freudenberg, A. Zieris, +6 authors C. Werner … new orleans fest joliet