Early endosome antigen 1

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August undefined, 2024

WebEarly endosomes are a major cytoplasmic sorting compartment from which receptors and ligands may be distributed to various sites within the cell. Early endosome antigen 1 (EEA1) is a 180 kDa hydrophilic peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence studies show that EEA1 colocalizes to early …

EEA1 early endosome antigen 1 [ Homo sapiens (human) ]

WebThe gene Early Endosome Antigen 1 (EEA1) encodes for around 1400 amino acid proteins. It is a peripheral membrane protein associated with the cytoplasmic face of early endosomes. EEA1 is a autoantigen associated with subacute cutaneous systemic lupus erythematosus and is a coiled-coil protein localized to early endosomes and cytosol. WebEndosomes are found in three forms: early endosomes, late endosomes, and recycling endosomes. The early endosomes develop into late endosomes, which then fuse with … dermafix online

Essential role of Ca2+/calmodulin in Early Endosome …

The gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate through its C-terminal FYVE domain and forms a homodimer … See more EEA1 is a RAB5A effector protein which binds via an N-terminal zinc finger domain and is required for fusion of early and late endosomes and for sorting at the early endosome level. See more Due to the proteins importance in vesicular trafficking, a number of intracellular bacteria prevent EEA1 recruitment to the vacuole. Mycobacterium tuberculosis is known to inhibit the … See more • early+endosome+antigen+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural … See more • endosome • Phosphatidylinositol 3-phosphate • FYVE domain See more WebMay 15, 2015 · Following entry into host cells, OMVs migrate to early endosome antigen 1 (EEA1)-labelled endosomes where they interact with and are detected by nucleotide-binding oligomerization domain ... WebMar 3, 2015 · To investigate whether GALNT1 regulates EGFR trafficking, immunofluorescence staining of GALNT1 knockdown HA22T and PLC5 cells treated with EGF 10 ng/ml was performed to analyze for co-localization of EGFR (red) with early endosome antigen 1 (EEA1) (green) or lysosomal associated membrane protein 1 … derma file for the skin

EEA1 Antibody (G-4) SCBT - Santa Cruz Biotechnology

Early Endosome Antigen 1 - an overview ScienceDirect Topics

WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in … WebEarly Endosome Antigen 1 Studies of EEA1 have been instrumental in defining the localization of PI(3)P. Closer examination of the protein reveals it is a large coiled-coil protein (Figure 138.3a) that can bind to the GTP-bound form of Rab5, a GTPase required for endosomal membrane fusion [17]. dermaflash 2.0 reviewsWebEEA1 Antibodies. Antibodies that detect EEA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, … chronological order of the conjuring

"WebCatalog FieldsAntigen: EEA1; Early endosome antigen 1Available to For-Profits: YesAntigen Species: HumanHybridoma Cells Available (Non-Profit): YesIsotype: … " - Early endosome antigen 1

Early endosome antigen 1

Purified Mouse Anti-EEA1 - BD Biosciences

WebSep 16, 2016 · Popular answers (1) The original characterization of "Early Endosomes" is defined by those compartments labeled by transferrin after 20 to 30 minutes of addition. EEA1 (early endosome antigen 1 ... WebSep 17, 2024 · The crucial effectors of Rab5 are early endosome antigen-1 (EEA1) [28, 29], rabaptin-5 [30, 31, 37], rabenosyn-5 [32, 38], APPL1/2 [33, 34], and ZFYVE21 (Table 1). EEA1, a key effector of Rab5 with a molecular weight of 162 kD, is a biomarker for early endosomes and has a parallel coiled-coil homodimer structure.

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WebDescription: The monoclonal antibody 1G11 recognizes human, mouse and rat early endosome antigen 1 (EEA1). EEA1 is a hydrophilic peripheral membrane protein found in the cytosol and present on early endosome membranes. EEA1 is a dimer that is localized to early endosomes via a cysteine-rich zinc-finger-like FYVE domain. WebEea1 early endosome antigen 1 [ (house mouse)] Gene ID: 216238, updated on 8-Nov-2024 Summary Predicted to enable 1-phosphatidylinositol binding activity; GTP …

WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in segments centered around amino acids 515 and 645. EEA1 contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for N … WebEEA1 early endosome antigen 1 [ (human)] Gene ID: 8411, updated on 8-Jan-2024 Summary Enables 1-phosphatidylinositol binding activity; GTP-dependent protein binding …

WebJul 9, 2024 · The derived amino acid sequence was found to be 99% identical to a 180 kd peripheral endosomal protein named early endosome antigen (EEA1). Results: … WebFeb 4, 2000 · Early endosome antigen 1 (EEA1) is 170-kDa polypeptide required for endosome fusion. EEA1 binds to both phosphtidylinositol 3-phosphate (PtdIns3P) and to …

Web3 hours ago · Our studies found that CRB3 could colocalize with EEA1-positive early endosomes, CD63-positive late endosomes and Rab11-positive recycling endosomes . In addition, after 2 hours of ... sequentially. Then, antigen retrieval was performed in Tris-EDTA buffer (pH 9.0) heated to 95°C for 20 min. Endogenous peroxidase activity was …

WebOct 1, 2013 · Early endosome antigen 1 (EEA1) is a peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence staining of EEA1 in macrophage cells yields punctuate staining pattern consistent with the cytoplasmic distribution of endosomes, but in a different way when compare uninfected-macrophages ( Fig. 2A ) in … chronological order of the book of jeremiahWebItem Monkey Early Endosome Antigen 1 ELISA Kit; Company MyBioSource.com; Price Pricing Info Supplier Page View Company Product Page; Catalog Number MBS051694; Quantity 96 Strip Wells; Applications ELISA; Reactivity Monkey; Detection Target Early Endosome Antigen 1 chronological order of the bourne moviesWebEarly endosome antigen 1 (EEA1) is 170-kDa polypeptide required for endosome fusion. EEA1 binds to both phosphtidylinositol 3-phosphate (PtdIns3P) and to Rab5-GTP in … dermaflash deviceWebJul 10, 2024 · At this stage, ingested materials can be recycled back to the plasma membrane, sent to the trans-Golgi Network (TGN), or degraded through endosomal acidification. Each compartment in the pathway is marked by characteristic proteins, such as early endosome antigen 1 (EEA1), lysosomal-associated membrane protein 1 … chronological order of the life of jesusWebEarly endosome antigen 1 (EEA1) is an early endosomal protein that contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for … chronological order of the tribulationWebMar 8, 2024 · d LgBiT-FYVE and Early Endosome Antigen 1. In both cases, secondary antibodies coupled with oligonucleotides (PLA probes) bind to the primary antibodies. When the PLA probes are in close proximity ... chronological order of the letters of paulWebMar 5, 2024 · EEA1 early endosome antigen 1 [Homo sapiens (human)] - Gene - NCBI NCBI Skip to main content Skip to navigation Resources All Resources Chemicals & … dermaflash cartridge