Cocaine- and amphetamine-regulated transcript
WebMar 1, 2012 · The cocaine- and amphetamine-regulated transcript (CART) peptidergic system is involved in processing diverse neuronal functions in adult animals, including energy metabolism. Although CART is widely distributed in the brain of a range of vertebrates, the ontogeny of this system has not been explored. The CART … WebMar 16, 1999 · Cocaine- and amphetamine-regulated transcript (CART) is a recently discovered hypothalamic peptide regulated by leptin and with a potent appetite-suppressing activity. In the rat, the CART gene encodes a peptide of 116 amino acid residues (or a splice variant 13 residues longer). The predicted signal sequence is 27 amino acid residues ...
Cocaine- and amphetamine-regulated transcript
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WebThe distribution of somatostatin and cocaine and amphetamine-regulated transcript (CART) was investigated in rat intracardiac ganglia. Somatostatin immunoreactivity was … WebCocaine- and amphetamine-regulated transcript (CART) peptides are novel neurotransmitters that are implicated in several physiological functions such as control of …
WebJul 8, 2002 · To date, cocaine- and amphetamine-regulated transcript (CART) peptides have been found to influence feeding, locomotor activity, and conditioned place preference. A common brain structure that could mediate these effects is … WebCART (cocaine- and amphetamine-regulated transcript) peptides are neuromodulators that are involved in feeding, drug reward, stress, cardiovascular function, and bone remodeling. CART peptides are abundant but discretely distributed in the brain, pituitary and adrenal glands, pancreas, and gut.
WebCocaine- and Amphetamine- Regulated Transcript (CART) is a neuropeptide produced in specific neurons in the hypothalamus - including in the arcuate nucleus.It plays a role in satiety, in association with leptin and neuropeptin Y; the former enhances satiety whereas the latter stimulates hunger.CART production has been shown to decrease in obese … WebCocaine- and amphetamine-regulated transcript is a recently discovered hypothalamic peptide that is co-expressed in POMC neurons, although its expression is not restricted …
WebCocaine and amphetamine‑regulated transcript (CART) is a neuropeptide that can protect brains against ischemic injury. The aim of the present study was to investigate the effects of the CART within ischemic stroke and it possible mechanism. The expression levels of dopamine (DA) and CART in ischemic …
WebCocaine- and Amphetamine-Regulated Transcript. CART (cocaine- and amphetamine-regulated transcript) is a neuropeptide that is expressed in most of the intake … tournament ranchWebNov 1, 2012 · Cocaine- and amphetamine-regulated transcript (CART) peptide is expressed by vagal afferent neurons. We sought to demonstrate that this neurotransmitter regulates CCK and leptin actions on short-term satiety. We also examined the signal transduction pathways responsible for mediating the CART release from the nodose … poulder inc 8864WebCocaine- and amphetamine-regulated transcript (CART) is a hypothalamic neuropeptide implicated in both metabolic and reproductive regulation, raising the possibility that CART plays a role in reproductive inhibition during negative metabolic conditions. poulefase wkWebJan 9, 2024 · Cocaine and amphetamine-regulated transcript prepropeptide gene (CARTPT) polymorphism interacts with Diet Quality Index-International (DQI-I) and Healthy Eating Index (HEI) to affect hypothalamic hormones and cardio-metabolic risk factors among obese individuals J Transl Med. 2024 Jan 9;18(1):16.doi: 10.1186/s12967-020-02208-z. … poulbot thionvilleWebApr 11, 2024 · Cocaine. and amphetamine-regulated transcript peptide (CARTp) is an anorexigenic neuropeptide whose receptor is undisclosed. Previously, we reported the specific binding of CART(61–102) to pheochromocytoma PC12 cells, where CART(61–102) affinity and the number of binding sites per cell corresponded to ligand-receptor binding. pouldreuzic distilrie whiskyWebMar 14, 2007 · The neuropeptide transmitter cocaine- and amphetamine-regulated transcript (CART) inhibits food intake and is expressed by both vagal afferent and hypothalamic neurons. Here we report that cholecystokinin (CCK) regulates CART expression in rat vagal afferent neurons. Thus, CART was virtually undetectable after … pouleedsfax homeoffice.gov.ukWebApr 24, 2014 · Cocaine and amphetamine-regulated transcript is a neuropeptide which appears to be a powerful physiological anorexic signal. CART mRNA was identified on the basis of its increase following cocaine or amphetamine treatment in rats . CART peptide is localized in specific areas of the hypothalamus including the periventricular nucleus, … tournament regulation chess board